Projects
Research grants
Members of the Laboratory of Biological Sensitizers are currently (in 2023) working on the following projects:
NCN (National Science Centre) grants:
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CEUS-UNISONO " Radiosensitizing derivatives of pyrimidine or purine nucleobases: Mass spectrometry and quantum chemical studies on low-energy electron interactions in gas phase, water clusters and solutions "
Principal investigator: Janusz Rak
Researchers: Lidia Chomicz-Mańka, Magdalena Datta, Samanta Romanowska, Adrian Szczyrba, Magdalena Zdrowowicz-Żamojć
The project is carried out in cooperation with groups from the Gdańsk University of Technology and the group of prof. Stephan Denifl from the University of Innsbruck
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PRELUDIUM 15 " Modeling phosphorylation by human thymidine kinase 1. A crucial step in the rational design of thymidine-analogue radiosensitizers"
Principal investigator: Samanta Romanowska
Scientific supervisor: Janusz Rak -
SONATA 17 „Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of radiotherapy”
Principal investigator: Magdalena Zdrowowicz-Żamojć
Young Scientists Researches grants (BMN) 2023:
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„Halogenothionucleoside derivatives as photosensitizers - mechanistic studies in the cellular environment”
Principal investigator: Anna Czaja -
„In vitro studies of the radiosensitizing properties of 8-trifluorooxobenzylamino-2'-deoxyadenosine”
Principal investigator: Magdalena Datta -
„Study on the DEA process and QSPR (Quantitative Structure-Property Relationship) analysis of mono-substituted bezyladenine derivatives as potential new purine-based radiosensitizers”
Principal investigator: Adrian Szczyrba
Computational grant:
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Wroclaw Centre for Networking and Supercomputing grant. "Electron impact on brominated DNA nucleotides"
Principal investigator: Lidia Chomicz-Mańka